Original Article Picroside II ameliorates acute liver
GalN injection. It was found that the survival rate in the control group was 100% vs. 25% in LPS/D-GalN group. Pretreatment with Picro II significantly improved the survival rate of LPS/ D-GalN group (*P<0.05, **P<0.01; Figure 1A). To determine the effect of Picro II against hepatic injury, serum ALT and AST levels were determined.